Supply Bulk Price Hormones CAS:171596-29-5 Tadalafil Powder Cialis WA:0086 15832901912
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Supply Bulk Price Hormones CAS:171596-29-5 Tadalafil Powder Cialis WA:0086 15832901912
Common Name:Tadalafil
Synonyms: Cialis
CAS Number171596-29-5
Molecular Weight389.404
Density1.5±0.1 g/cm3
Boiling Point679.1±55.0 °C at 760 mmHg
Molecular FormulaC22H19N3O4
Melting Point298-300ºC
Flash Point364.5±31.5 °C
SymbolGHS02 GHS07
Purity 99%
Exact Mass389.137543
PSA74.87000
LogP1.43
Vapor Pressure0.0±2.1 mmHg at 25°C
Index of Refraction1,758
Storage conditionHygroscopic, -20?C Freezer, Under Inert Atmosphere
Use of Cialis
Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.IC50 Value: 1.8±0.4nM [1]Target: PDE 5Tadalafil is marketed in pill form for treating erectile dysfunction(ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension. Tadalafil can elevate the level of cGMP in the corpus cavernosum and effectively improve ED of various causes and degrees.
Tadalafil Usage And Synthesis
DescriptionTadalafil (market name "Cialis" or "Adcirca") was developed by the American pharmaceutical company Lilly. It is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessel muscles and increasing the blood flow into the corpus cavernosum. Studies show that Cialis works very quickly, taking effect in around 15-20 minutes, and has a prolonged effect that can last for up to 36 hours. T1/2 is 17.5h.
Chemical PropertiesWhite to Off-White Cyrstalline Powder
UsesTadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
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