Supply Bulk Price Hormones CAS:171596-29-5 Tadalafil Powder Cialis WA:0086 15832901912
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Supply Bulk Price Hormones CAS:171596-29-5 Tadalafil Powder Cialis WA:0086 15832901912
Common Name:Tadalafil
Synonyms: Cialis
CAS Number 171596-29-5
Molecular Weight 389.404
Density 1.5±0.1 g/cm3
Boiling Point 679.1±55.0 °C at 760 mmHg
Molecular Formula C22H19N3O4
Melting Point 298-300ºC
Flash Point 364.5±31.5 °C
Symbol GHS02 GHS07
Purity 99%
Exact Mass 389.137543
PSA 74.87000
LogP 1.43
Vapor Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.758
Storage condition Hygroscopic, -20?C Freezer, Under Inert Atmosphere
Use of Cialis
Tadalafil is a PDE5 inhibitor with an IC50 value of 1.8 nM.IC50 Value: 1.8±0.4nM [1]Target: PDE 5Tadalafil is marketed in pill form for treating erectile dysfunction(ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension. Tadalafil can elevate the level of cGMP in the corpus cavernosum and effectively improve ED of various causes and degrees.
Tadalafil Usage And Synthesis
Description Tadalafil (market name "Cialis" or "Adcirca") was developed by the American pharmaceutical company Lilly. It is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessel muscles and increasing the blood flow into the corpus cavernosum. Studies show that Cialis works very quickly, taking effect in around 15-20 minutes, and has a prolonged effect that can last for up to 36 hours. T1/2 is 17.5h.
Chemical Properties White to Off-White Cyrstalline Powder
Uses Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
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